Manuela Leri about Amytracker 630
"I used the Amytracker 630 probe to visualize intracellular aggregates on cell cultures. I obtained excellent results using confocal microscopy. The cells were permeabilized and the probe recognized the primary antibody used very well and emitted a good signal. The signal is stable."
Manuela Leri (PhD) Postdoctoral Researcher, Department of Experimental and Clinical Biomedical Sciences, University of Florence, Italy
SH-SY5Y neuroblastoma cells were treated with okadaic acid (LEFT) to induce hyperphosphorylation of Tau. Control cells (RIGHT) were left untreated. Amytracker 630 was used to label aggregates emerging in live cells. Images were kindly provided from Manuela Leri (PhD), Postdoctoral Researcher at the Department of Experimental and Clinical Biomedical Sciences, University of Florence, Italy.